About this game

St. Louis Cardinals vs Chicago Cubs Final Score, Odds & Picks

MLB · Friday, September 26, 2025, 2:21 PM ET · Wrigley Field, Chicago, Illinois · TV: Marquee Sports Net

Final: St. Louis Cardinals 1, Chicago Cubs 12.

Series: CHC win series 5-1.

Records: St. Louis Cardinals 78-82, Chicago Cubs 90-70.

Cardinals vs Cubs scoring plays

Final: Cardinals 1, Cubs 12 · 4:59 PM ET · Chicago Cubs beat St. Louis Cardinals 12-1.
Cubs score: Cardinals 1, Cubs 12 (Bottom 8th) · 4:51 PM ET · Alcántara singled to right, Ballesteros scored.
Cubs score: Cardinals 1, Cubs 11 (Bottom 7th) · 4:30 PM ET · Suzuki homered to left center (392 feet), Hoerner scored, Happ scored and Tucker scored.
Cubs score: Cardinals 1, Cubs 7 (Bottom 7th) · 4:24 PM ET · Happ reached on infield single to shortstop, Busch scored, Hoerner to second.
Cubs score: Cardinals 1, Cubs 6 (Bottom 7th) · 4:18 PM ET · Busch doubled to right, Shaw scored.
Cubs score: Cardinals 1, Cubs 5 (Bottom 7th) · 4:15 PM ET · Shaw tripled to left, Swanson scored.
Cardinals score: Cardinals 1, Cubs 4 (Top 7th) · 4:04 PM ET · Walker singled to left, Gorman scored, Saggese to second.
Cubs score: Cardinals 0, Cubs 4 (Bottom 5th) · 3:28 PM ET · Busch homered to center (414 feet).
Cubs score: Cardinals 0, Cubs 3 (Bottom 4th) · 3:12 PM ET · Crow-Armstrong homered to right center (396 feet), Tucker scored.
Cubs score: Cardinals 0, Cubs 1 (Bottom 1st) · 2:26 PM ET · Hoerner homered to center (412 feet).

Spread: Chicago Cubs -10.5 (-5100) · St. Louis Cardinals +10.5 (+1100)

Total: Over 13.5 (+1100) · Under 13.5 (-5100)

1 pick on Picksy: Cubs ML; 1 won, 0 lost.

The Chicago Cubs beat the St. Louis Cardinals 12-1 on Friday, September 26, 2025.

The Chicago Cubs were favored at DraftKings: -10.5 on the run line.

The total was 13.5 runs at DraftKings (over +1100, under -5100). The game finished with 13, under the total.

1 pick on Picksy: Cubs ML; 1 won, 0 lost.