About this game
Chicago White Sox vs Cleveland Guardians Final Score, Odds & Picks
MLB · Wednesday, September 16, 2026, 1:00 PM ET · Progressive Field, Cleveland, Ohio · TV: ESPN
Final: Chicago White Sox 3, Cleveland Guardians 6.
Series: CLE wins series 2-1.
Records: Chicago White Sox 77-75, Cleveland Guardians 78-75.
White Sox vs Guardians scoring plays
- Final: White Sox 3, Guardians 6 · 3:45 PM ET · Cleveland Guardians beat Chicago White Sox 6-3.
- Guardians score: White Sox 3, Guardians 6 (Bottom 6th) · 3:00 PM ET · Ramírez doubled to left, Rocchio scored, Kwan to third.
- Guardians score: White Sox 3, Guardians 5 (Bottom 6th) · 2:53 PM ET · Halpin homered to right center (393 feet), Fry scored and Hedges scored.
- White Sox score: White Sox 3, Guardians 2 (Top 5th) · 2:27 PM ET · Pham homered to left center (412 feet), Meidroth scored and Grichuk scored.
- Guardians score: White Sox 0, Guardians 2 (Bottom 3rd) · 1:57 PM ET · Adell singled to left, Halpin scored and Kwan scored.
Chicago White Sox vs Cleveland Guardians picks
1 pick on Picksy: Guardians ML; 1 won, 0 lost.
White Sox vs Guardians: questions & answers
Who won White Sox vs Guardians?
The Cleveland Guardians beat the Chicago White Sox 6-3 on Wednesday, September 16, 2026.
What are the picks for White Sox vs Guardians?
1 pick on Picksy: Guardians ML; 1 won, 0 lost.