Cleveland Guardians vs Boston Red Sox Final Score, Odds & Picks
MLB · Tuesday, September 22, 2026, 6:45 PM ET · Fenway Park, Boston, Massachusetts · TV: MLB.TV
Final: Cleveland Guardians 3, Boston Red Sox 2.
Series: CLE wins series 2-1.
Records: Cleveland Guardians 82-75, Boston Red Sox 84-73.
Guardians vs Red Sox scoring plays
Final: Guardians 3, Red Sox 2 · 9:42 PM ET · Cleveland Guardians beat Boston Red Sox 3-2.
Guardians score: Guardians 3, Red Sox 2 (Top 9th) · 9:27 PM ET · Lowe hit sacrifice fly to left, DeLauter scored.
Red Sox score: Guardians 2, Red Sox 2 (Bottom 8th) · 9:13 PM ET · Gasper homered to right (390 feet).
Red Sox score: Guardians 2, Red Sox 1 (Bottom 2nd) · 7:20 PM ET · Monasterio grounded out to shortstop, Rutschman scored.
Guardians score: Guardians 2, Red Sox 0 (Top 2nd) · 7:08 PM ET · Rocchio grounded into double play, second to shortstop to first, Fry scored, Hedges out at second, Bazzana to third.
Guardians score: Guardians 1, Red Sox 0 (Top 2nd) · 7:04 PM ET · Fry singled to center, Martínez scored.
Cleveland Guardians vs Boston Red Sox picks
4 picks on Picksy, most on Under 0.5 (1st Inning) (1 of 4); 1 won, 3 lost.